Denise Giuvelis, Nicholas McGlinchey and Ed Bilsky publish research article in ‘Journal of Medicinal Chemistry’

Three members of the Bilsky laboratory are co-authors on a recent article published in the Journal of Medicinal Chemistry. The paper, titled “14-Alkoxy- and 14-Acyloxypyridomophinans: Mixed Mu Agonist/Delta Antagonist Opioid Analgesics with Diminished Tolerance and Dependence Side Effects” investigated novel compounds for the treatment of acute and chronic pain.

The team that carried out the project included ɫƵ staff member Denise Giuvelis (’07), current COP student and CAS alum Nicholas McGlinchey and Edward Bilsky, Ph.D., associate provost for research and scholarship and professor of biomedical sciences in COM. The work was done in collaboration with long-time colleagues at Southern Research Institute and the National Institute on Drug Abuse.

Citation: Ananthan, S., Saini, S.K., Dersch, C.M., Xu, H., McGlinchey, N., Giuvelis, D., Bilsky, E.J. and Rothman, R.B. 14-Alkoxy- and 14-Acyloxypyridomophinans: Mixed Mu Agonist/Delta Antagonist Opioid Analgesics with Diminished Tolerance and Dependence Side Effects. Journal of Medicinal Chemistry. E-pub, September 2012.
 

About the University of New England

The ɫƵis Maine’s largest independent university, with two beautiful coastal campuses in Maine, a one-of-a-kind study abroad campus in Tangier, Morocco, and an array of . In an uncommonly welcoming and supportive community, we offer hands-on learning, empowering students to make a positive impact in a world full of challenges. The state’s top provider of health professionals, we are home to Maine’s only medical college, Maine’s only dental college, a variety of other interprofessionally aligned health care degree programs, as well as nationally recognized programs for marine science degrees, natural and social sciences degrees, arts and humanities degrees, and business degrees.